Overview of Pulmonary Capillary Wedge Pressure
Pulmonary capillary wedge pressure (PCWP) is a measure often used by doctors to gauge how well the left side of your heart is working, especially the left atrium and the mitral valve (a valve in your heart). This measurement is taken with a special device called a Swan-Ganz catheter. The process involves inserting this device into one of your veins and then moving it into a branch of your lung’s artery. A tiny balloon on the device is then inflated to block off the artery. The pressure that’s then measured is essentially what the pressure in your left atrium is.
Right heart catheterization (RHC) is a procedure that involves inserting a device into your heart to make similar assessments. It has to be done by experts and needs careful monitoring. This method was initially described in the 18th century. Since then, it has evolved significantly. However, its use has gone down because several studies found that it did not show benefits in patients with severe heart failure or those in a state of cardiogenic shock, which is a condition where your heart suddenly can’t pump enough blood to meet your body’s needs. Despite this, RHC remains essential in diagnosing, assessing the severity, and managing patients suspected to have pulmonary hypertension (high blood pressure in the arteries in your lungs) and certain heart failure patients.
Anatomy and Physiology of Pulmonary Capillary Wedge Pressure
To measure the pressure in your heart’s pulmonary capillaries (small blood vessels), a special tube called a catheter is inserted into one of your larger veins. This vein might be in your leg (femoral), just below your collarbone (subclavian), or in your neck (internal jugular), with the jugular vein being the preferred choice. The catheter is then guided into a large vein leading back to your heart and from there into the right upper chamber (atrium) of your heart.
From the right atrium, the catheter is guided through a heart valve (the tricuspid valve) into the right lower chamber, or ventricle, of the heart. It is then pushed further and guided into the area where the right ventricle pumps blood to the lungs (pulmonary artery). There, a small balloon attached to the catheter can be inflated to take measurements of the pressure, called the pulmonary capillary wedge pressure (PCWP).
PCWP gives us a rough estimate of the pressure in the left ventricle of the heart at the time it is filling with blood (left ventricular end-diastolic pressure). Normal PCWP ranges from 4 to 12 mmHg. If it’s higher than that, it might mean there are problems with your heart, like severe failure of the left ventricle or harsh narrowing of the valve in your heart called the mitral valve (severe mitral stenosis).
How do we know where the catheter is at any point in time? The answer is simple: by looking at the shape of the signal seen on the monitor which is produced as the catheter tip measures pressure, and by measuring the pressure in both systole (when the heart contracts) and diastole (when the heart relaxes). For example, in the right atrium, both the systolic and diastolic pressures are usually less than 5 mmHg. In the right ventricle, the systolic pressure is about 25 mmHg, while the diastolic pressure remains similar to the right atrial diastolic pressure (<5 mmHg). In contrast, the diastolic pressure in the pulmonary artery rises to about 10 mmHg.
Why do People Need Pulmonary Capillary Wedge Pressure
Measuring the Pulmonary Capillary Wedge Pressure (PCWP) is a medical procedure used for various reasons. Here are some of the main ones:
- It helps doctors tell the difference between two types of fluid buildup in the lungs: one caused by heart problems (cardiogenic pulmonary edema) and the other not related to the heart (noncardiogenic pulmonary edema).
- It is used to confirm if a patient has high blood pressure in the lungs’ arteries, known as pulmonary arterial hypertension.
- It helps in assessing the severity of a heart valve problem called mitral stenosis, which restricts the flow of blood from the heart to the rest of the body.
- It aids in distinguishing between various forms of shock, which is a serious health condition that happens when the body is not getting enough blood flow and can lead to organ failure or death.
- Lastly, it is used to measure important indicators of the heart’s function and evaluate how well a therapy or treatment is working.
So measuring PCWP is a critical tool in diagnosing and managing a variety of heart and lung conditions.
When a Person Should Avoid Pulmonary Capillary Wedge Pressure
There are certain situations where it’s not safe or possible to undergo a particular medical procedure. These are known as contraindications. For instance, there are a few extreme cases which may prevent a heart procedure:
– If there is an infection (endocarditis) or tumors on the right side of the heart, it’s not safe to do the procedure.
– The same applies if the patient does not give their consent for the procedure.
Similarly, there are some less severe, or ‘relative’, contraindications. These may require some additional cautions or alternative approaches:
– If there are issues with the tricuspid or pulmonary valves, two important parts of the heart, extra care must be taken.
– If the patient has a left bundle branch block – a condition that slows down the electrical signals that make the heart beat – there is a risk of causing a complete heart block that might stop these signals. This would need to be carefully considered before proceeding.
Equipment used for Pulmonary Capillary Wedge Pressure
The PA catheter, also known as the Swan-Ganz catheter, is a special tube that doctors commonly use for various medical procedures. It is a long tube, usually about 60 to 110 cm, and is quite thin, about 4 to 8Fr in measurement. The names “Swan” and “Ganz” refer to Jeremy Swan and William Ganz, the inventors of this catheter.
In most cases, the catheter has four different channels or “lumens.” Each lumen performs a specific function:
* The proximal lumen (also referred to as the blue port) is usually found in the right atrium (one of the chambers in the heart), where it measures pressure. This lumen can also be used for giving medications, and on certain PA catheters there may be a special lumen just for this use.
* The distal lumen (or yellow port) is at the far end of the catheter, resting in the pulmonary artery. This part is for tracking the pressures in your pulmonary artery and for getting a mixed venous sample, which is a special type of blood sample. It’s important to note that medications and infusions should not be given through this port.
The catheter also includes a specific part for balloon inflation and deflation located on its red port. The balloon itself is located about 2 cm from the far end of the catheter. Each PA catheter comes with a syringe of 1.5 ml used specifically for inflating or deflating the balloon. This balloon is important for guiding the catheter through the heart and into the PA following the direction of the blood flow. When inflated, it also helps in measuring the Pulmonary Capillary Wedge Pressure (PCWP), which is an important measurement for doctors.
Finally, this catheter can even measure the core temperature in the pulmonary artery using a device known as a thermistor. This information is particularly important in determining the cardiac output (how much blood the heart is pumping), assessed using an approach called the thermodilution method.
How is Pulmonary Capillary Wedge Pressure performed
Before any medical procedure, a series of checks, known as a “time-out”, are completed to ensure patient safety. This “time-out” includes confirming the patient’s details, the planned procedure and its location, the patient’s consent, latest lab results and current medications, as well as making sure the right medical team and equipment are present. Typically, for a Right Heart Catheterization (RHC), the primary vein used for access is the internal jugular vein which is located in the neck. An ultrasound image may be used to help the medical team find the vein and to confirm that there’s no clot present.
The procedure begins with the medical team cleaning the area with a antiseptic solution and then setting up a sterile work area to prevent infection. After reconfirming the vein’s location with an ultrasound, local anesthesia is applied to numb the area. A needle is then used to puncture the vein, after which a guidewire is inserted into the vein. Removal of the needle then follows, and a small cut is made to allow a dilator, a device that widens the opening, to be inserted. The dilator and guidewire are then removed, leaving behind a sheath in the vein.
A pulmonary artery (PA) catheter is then inserted through the sheath and moved along until it reaches the right atrium of the heart, which can be verified on a monitor. Once placement is confirmed, a balloon on the catheter is inflated and the catheter is advanced into the right ventricle and then into the pulmonary artery. The balloon is deflated, and the pressure of the pulmonary artery can be measured. The balloon is re-inflated to seal off a portion of the artery and create a column of blood between the artery and the pulmonary vein. This pressure is called the Pulmonary Capillary Wedge Pressure (PCWP) and it helps the medical team estimate the pressure in the left heart vessels. Once the procedure is done, a chest X-ray would be ordered to ensure the catheter is in the right position.
Completeness and accuracy of the data obtained during the procedure is crucial. This data includes measurement of oxygen saturation, right atrial and right ventricular pressures, pulmonary artery pressure, left heart filling pressure, heart output and heart rate, systemic blood pressure, response to acute vasodilators and more. Misinterpretation of the wedge pressure is a common obstacle in diagnosing pulmonary hypertension, which is high blood pressure in the blood vessels of the lungs. The measurement should be taken at end-expiration and in different parts of the pulmonary vasculature.
Possible Complications of Pulmonary Capillary Wedge Pressure
Placing a catheter into the pulmonary artery is a more sophisticated process, which naturally comes with its own set of risks. According to various studies, about 5% to 10% of people face some problems after this operation.
Here are a few common issues that may arise from this surgery:
1. Arrhythmias – This is when your heart rhythm becomes abnormal.
2. Thromboembolism – This is when a blood clot moves through the blood to block another vessel.
3. Pulmonary Ischemia – This happens when there is not enough blood flow to the lungs.
4. Hemoptysis – This is when you cough up blood.
5. Pulmonary Hemorrhage – This is massive bleeding in the lungs.
6. Pulmonary Artery Perforation – This is when a hole is made in the pulmonary artery.
7. Knotting of the Catheter – This is when the thin tube that was inserted twists or tangles.
8. Arterial Puncture – This is when a hole is accidentally made in an artery.
9. Hematoma – This is when blood accumulates outside of the blood vessels.
10. Local Infection – This is an infection that occurs near the site where the surgery was performed.
All these issues can happen during or after the procedure.
What Else Should I Know About Pulmonary Capillary Wedge Pressure?
The PCWP, or Pulmonary Capillary Wedge Pressure, is a useful tool doctors use to measure pressure in your heart. Think of it like a car’s pressure gauge. It can tell doctors how your left heart chamber is performing, and the state of the mitral valve, which controls the flow of blood in the heart.
By measuring PCWP, your doctor can work out what dosage of medication to give you. If you have too much pressure in your chest, which can lead to a condition called pulmonary edema (where fluid accumulates in the lungs, making it difficult to breathe), this measurement can help your doctor adjust your medication to alleviate it.
Doctors also use PCWP measurements to understand and diagnose a condition called Pulmonary Arterial Hypertension (PAH), a type of high blood pressure that affects the arteries in your lungs and the right side of your heart. Patients with group 1 PAH will have a PCWP measurement of 15 mmHg or less.
PCWP is also used to work out how much blood is flowing through your lungs.
Additionally, PCWP measurements play a role in identifying what type of shock a patient is experiencing – cardiogenic (originating in the heart) or non-cardiogenic (not originating in the heart). If a patient is experiencing low blood pressure shock, the doctor will use the PCWP measurement to determine how much fluid the patient needs, aiming to maintain a PCWP between 12 to 14 mmHg.