What is Pediatric Appendicitis?
Appendicitis is a condition where the appendix becomes suddenly inflamed. This condition is the top reason for emergency surgery and is often the cause behind stomach pain, especially in kids. If anyone experiences sudden stomach pain and they still have their appendix, appendicitis could be the cause. It’s crucial to diagnose appendicitis quickly because the longer it’s left untreated, the higher the chance of the appendix bursting becomes.
What Causes Pediatric Appendicitis?
Appendicitis is caused when there’s a blockage in the appendix. This blockage can occur because of either inflammation of the appendix’s inner lining (its wall) or a hard piece of stool, known as a fecalith.
The blockage can also be due to hardened deposits within the appendix, known as appendicoliths. Another cause can be lymphoid hyperplasia. This is when the lymphoid tissues (the cells that help your body fight off infection) within the appendix, located in its inner and middle layers (mucosa and submucosa), swell or grow excessively. This overgrowth can cause a blockage in the appendix, leading to appendicitis.
Risk Factors and Frequency for Pediatric Appendicitis
Every year, there are as many as 250,000 cases of appendicitis reported. The chance of having appendicitis in your lifetime is estimated at 12% for males and 25% for females. While appendicitis can happen at any age, it is most common in people between 10 and 19 years old.
Signs and Symptoms of Pediatric Appendicitis
Appendicitis is a condition that causes severe pain in the stomach. It usually starts with pain around the middle of the stomach, which then moves to the lower right side. If you feel like throwing up, it normally happens after the pain begins. You might also feel a burning sensation when you pee, or even find blood in your urine because the inflamed appendix is close to your urinary tract. Even though it is common to lose appetite, not everyone experiences it.
Keep in mind that these standard symptoms might not always be the case, especially in children. It’s common for them to experience unclear or strange symptoms such as widespread stomach pain, possibly with vomiting, and a mild fever. Diarrhea can also be a symptom, and this can make it difficult to identify if it’s appendicitis or just a common stomach bug.
The kind of symptoms you experience can also depend on the specific location of the inflamed appendix:
- If the appendix is located behind the large intestine, it might cause back or side pain.
- If it is in the pelvic area, it can cause upper pubic pain.
- If the appendix is unusually long, it can cause pain in the upper right or lower left-side of the stomach.
During a physical check-up, doctors usually look for tenderness in the lower right part of your stomach. This area is most sensitive due to the condition and is a helpful clue for diagnosis.
Other signs include a sharp pain in the lower right side when the left side is prodded (Rovsing’s sign), more pain in the lower right side when the right leg is extended while laying on the left side (Psoas sign), and increased pain in the lower right side when the right leg is rotated while laying flat (Obturator sign).
However, one important thing to remember is that these symptoms alone don’t confirm or deny appendicitis. Additionally, a rectal examination doesn’t provide any extra information about the condition.
No single symptom or physical sign can confirm or rule out appendicitis on its own.
Testing for Pediatric Appendicitis
Doctors often rely on laboratory tests along with the patient’s medical history and physical exam results for diagnosing various conditions. Even though lab results can strengthen the diagnosis made on the basis of symptoms, these cannot replace a detailed discussion about symptoms and a thorough physical check-up.
Your doctor might ask for a white blood cell count (WBC) to understand if there’s inflammation in your body. But solely based on WBC, appendicitis can’t be confirmed or ruled out. This is because many other conditions like stomach flu, inflammation of lymph nodes in the stomach, pelvic inflammatory disease, among others, can also increase WBC. Even in appendicitis, WBC might be normal.
A urine test is generally normal but may show changes if the swollen appendix is close to the bladder or ureter (the tube carrying urine from kidney to bladder).
Diagnosing appendicitis depends a lot on the symptoms and examination by the doctor. Imaging tests may not always be required, especially when the doctor can make a diagnosis by your symptoms and physical examination. If you have typical symptoms of appendicitis, your doctor may ask for a surgeon’s opinion before ordering any tests. They won’t delay consultation for tests.
Ultrasound (US) is being frequently used, especially in kids where there’s a high need to avoid radiation. While ultrasound is less costly and doesn’t involve radiation, the results are dependent on the expertise of the operator. If an inflamed appendix, thicker than 6 mm, is seen on ultrasound, it confirms appendicitis. If the ultrasound results are unclear, you may need to get a CT or an MRI, especially if you’re pregnant. A positive result can help avoid a CT scan. That said, if an ultrasound doesn’t show anything, it doesn’t necessarily rule out appendicitis. It may also be useful in excluding conditions like tubo-ovarian abscess in women of child bearing age.
When it comes to a detailed examination for tracing signs of appendicitis, a CT scan of the abdomen and pelvis is considered the best. Though, CT scans expose the body to radiation, which is a concern particularly with kids. Hence, doctors consider using this scan carefully. A CT scan can show:
- A swollen appendix that is more than 6 mm in size and has a thickened wall (more than 2 mm)
- Inflammation around the appendix
- Appendicolith (hardened fecal deposit in the appendix)
- Abscess or collection of pus in or near the appendix
- Free fluid
If the appendix is not seen in the scan, it does not necessarily rule out appendicitis.
Magnetic Resonance Imaging (MRI) is a valuable tool, especially for pregnant women and kids when ultrasound results are not clear. This is a better option as pregnant women should not be given intravenous (IV) contrast dye as it can cross the placenta and potentially harm the baby. Similarly, it should also not be used in people with poor kidney function.
There are some limitations to using MRI:
- It is more expensive
- Takes longer time to get images
- Requires a skilled radiologist to read the images
- May not be easily available
Also, MRI is not preferred for patients who are unstable and young children who may need sedation. Recently, the use of quick MRI without contrast or sedation has been studied for diagnosing appendicitis in kids.
Treatment Options for Pediatric Appendicitis
If your doctor believes you may have appendicitis, they will usually ask for advice from a surgeon as soon as possible. In order to prepare your body for possible surgery, your doctor will stop your food and drink intake. They may give you fluids through a vein in your arm to keep you hydrated.
Doctors also generally recommend the use of antibiotics to protect against both types of bacteria – those that require oxygen to survive (aerobic bacteria), and those that live and grow in areas where little or no oxygen is present (anaerobic bacteria). The timing of these antibiotics is crucial and will be carefully coordinated with the surgical team to ensure that the level of antibiotic in your body is at its peak during the operation.
You’ll also receive pain relief medication, as appendicitis can be very painful. If the appendix has burst and caused an infection that has spread to other parts of your body (perforated appendicitis), doctors may use different types of antibiotics.
Surgery is the main treatment for appendicitis. You, your family, and your doctors will discuss the benefits and risks of surgery. A traditional open surgery or a laparoscopic surgery, where small cuts are made and a camera is used to guide the surgeon, could be performed depending on the surgeon’s expertise and the available equipment.
Laparoscopic surgery is usually preferred because it causes less pain, allows for quicker recovery, shorter hospital stays, and has a lower risk of infection. In some cases, especially with children, a minimally invasive technique called Transumbilical Laparoscopic Assisted Appendicectomy may be used. Another method, the laparoscopic-assisted single-port appendectomy (SPA), has been found to be safe in children, although it is not yet considered the default method for appendicitis surgery.
What else can Pediatric Appendicitis be?
There are several conditions that might mimic the symptoms of other diseases, making it challenging for physicians to pin down an accurate diagnosis. These conditions include:
- Intussusception
- Meckel diverticulum
- Ectopic pregnancy
- Testicular torsion
- Kidney stones
- Viral and bacterial gastroenteritis
- Pelvic Inflammatory Disease (PID)
Possible Complications When Diagnosed with Pediatric Appendicitis
- Rupture of the appendix
- Sudden drop in blood pressure
- Abscess or pocket of infection in the pelvic region
- Infection in the wound from surgery
- Blockage in the intestines